Analysis of Orthopedic Surgery for Long Bone Metastases and Pathologic Fractures
A. I. Radchenko *
N. N. Alexandrov National Cancer Centre, Minsk, Belarus
A. G. Zhukovets
Department of Oncology, Belarusian Medical Academy of Post-Graduate Education, Minsk, Belarus
Y. M. Bogdayev
N. N. Alexandrov National Cancer Centre, Minsk, Belarus
*Author to whom correspondence should be addressed.
Abstract
The study made a retrospective analysis of treatment outcomes in 105 patients subjected to 128 surgical interventions for metastatic involvement of long tubular bones. Endoprosthetic replacement of large joints (40.2%) and intramedullary osteosynthesis (29.7%) were the main types of surgical interventions. The postoperative morbidity rate was 24.2%.The treatment administered made it possible to preserve extremity functioning in 85.7% of the patients and to significantly improve their quality of life, with one-year survival rate being 62.0%, 3-year – 28.5%, 5-year – 11.4%. Lung cancer, the presence of visceral metastases and the time of distant metastasis development were proved to be the unfavourable prognostic factors.
Keywords: Long bone metastases, surgical treatment, quality of life, functional result