Giant Keratoacanthoma Centrifugum Marginatum: A Rare Case Report with Note on Literature Review
Stuti Chhawchharia
Department of Dermatology, Venereology and Leprosy, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, India.
Amar Singh *
Department of Dermatology, Venereology and Leprosy, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, India.
Amit Rana
Department of ENT, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, India.
Mamta Verma
Department of ENT, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Keratoacanthoma Centrifugum Marginatum (KCM) is a rare variant of keratoacanthoma that closely mimics squamous cell carcinoma (SCC), posing significant diagnostic challenges.
Case Report: A 45-year-old male presented with a progressively enlarging hyperkeratotic lesion on the right cheek. Histopathological examination revealed pseudocarcinomatous hyperplasia with a central keratin plug, and MRI confirmed the lesion was confined to subcutaneous tissues without deeper invasion. Surgical excision was advised.
Conclusion: This case highlights the importance of distinguishing KCM from SCC to prevent overtreatment. Surgical excision remains the preferred treatment, complemented by regular postoperative follow-ups for recurrence monitoring.
Keywords: Keratoacanthoma centrifugum marginatum, pseudocarcinomatous hyperplasia, squamous cell carcinoma mimic, surgical excision