Epidemiomorphology of Prostate Cancer in Cameroon: About 1047 Cases
Jean Paul Ndamba Engbang *
Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon and Laquintinie Hospital of Douala, Douala, Cameroon and North-Ossetian State Medical Academy, Vladikavkaz, Russia
Beyeme Sala
Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon and Laquintinie Hospital of Douala, Douala, Cameroon
Herve Moby
Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon and Regional Hospital Annex of Nkongsamba, Nkongsamba, Cameroon
Yoan Ligan
Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon
Bruno Djougmo Djimeli
Laquintinie Hospital of Douala, Douala, Cameroon
Godefroy Simo
Bio-Medical and Cancer Center of Bafoussam, Bafoussam, Cameroon
André Moune
Anapathos Laboratory, Douala, Cameroon
Albert Sone Mouelle
Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, Douala, Cameroon and Douala General Hospital, Douala, Cameroon
Amadou Fewou
Douala General Hospital, Douala, Cameroon and Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon
Jean Louis Oyono Essame
Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon and Yaounde University Health Center, Yaoundé, Cameroon
Alan Hasigov
North-Ossetian State Medical Academy, Vladikavkaz, Russia
*Author to whom correspondence should be addressed.
Abstract
Objective: To determine the epidemiological and histological profile of prostate cancer in Cameroon.
Materials and Methods: It was a descriptive and retrospective study over a period of 12 years (2004-2015), concerning prostate cancers in five regions (Center, Littoral, West, North-west South-west). The studied parameters were frequency, age, PSA, histological type and Gleason score.
Results: We collected 1047 prostate cancers, which represented 81.42% of all urogenital cancers. The average age was 66.88 ± 9.58 years (range 32–98 years). The most affected age group was 60-79 years (736 cases), however, 3.15% (33 cases) were under 50 years. Histologically, we found a predominance of adenocarcinoma with 1044 cases (99.71%). Moderately differentiated tumors (Gleason score 7-8) represented the majority 56.56% (590 cases) of cases.
Conclusion: Prostate cancers are the predominant malignant uro-genital tumors in Cameroon. We noted the significant presence of relatively young men. Adenocarcinoma is still the main histological type. Moderately differentiated tumors are the most common.
Keywords: Cancer, prostate, epidemiology, histopathology, Cameroon