Radiation - Induced Sarcoma: A Case Report
K. Diabate *
Department of Radiotherapy, National Institute of Oncology, University of Mohamed V Soussi, Rabat, Morocco
H. Bakkali
Department of Radiotherapy, National Institute of Oncology, University of Mohamed V Soussi, Rabat, Morocco
T. Kebdani
Department of Radiotherapy, National Institute of Oncology, University of Mohamed V Soussi, Rabat, Morocco
B. K. El-Gueddari
Department of Radiotherapy, National Institute of Oncology, University of Mohamed V Soussi, Rabat, Morocco
N. Benjaafar
Department of Radiotherapy, National Institute of Oncology, University of Mohamed V Soussi, Rabat, Morocco
*Author to whom correspondence should be addressed.
Abstract
Objective: Study the epidemiology, histology, time to onset, treatment and prognosis of radiation induced sarcomas.
Observation: We report a case of sarcomas occurring in irradiated area, in a patient treated by external radiotherapy for left orbit cancer
Discussion: Few series of induced radiation sarcoma of the cervical and facial region have been published these over the last twenty last years. Their prevalence is low; several factors are recognized in their carcinogenesis. Genetic predisposition; chemotherapy and radiotherapy.
Conclusion: Radiation therapy can induce cancer after a latency period of several years. The risk is low but increases proportionately a longer period of treatment. These radiation induced sarcomas have generally an unfavorable prognosis and their treatment is primarily with surgery.
Keywords: Sarcoma, radiotherapy, orbit cancer